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Roche Tecentriq, chemotherapy combo wins USFDA approval for treatment of lung cancer


Roche Tecentriq, chemotherapy combo wins USFDA approval for treatment of lung cancer

New Delhi: Swiss drugmaker Roche Holding AG’s U.S. unit Genentech said on Monday its immunotherapy Tecentriq won approval for a tough-to-treat type of lung cancer, the latest win for the drug whose sales trail medicines from Merck & Co and Bristol-Myers Squibb.

The U.S. Food and Drug Administration (FDA) approved Tecentriq plus chemotherapy for untreated extensive-stage small cell lung cancer (SCLC) after a study showed patients getting the drug cocktail lived a median 12.3 months, compared to 10.3 months for those getting chemotherapy alone, Genentech said in a statement.

Read Also: Pfizer biosimilar to Roche Herceptin wins USFDA nod

About 10 to 15 per cent of lung cancers are small cell, or oat cell cancer, where tumours tend to spread very early. Advances in SCLC treatment have been slow in coming, and Roche has hailed Tecentriq as the first potential new first-line option in two decades.

The FDA’s decision on Monday follows approval of Tecentriq combinations in recent weeks for triple negative breast cancer and non-small cell lung cancer.

Read Also: Roche to buy Spark Therapeutics in Rs 430 crore deal

Tecentriq’s 2018 revenue were 772 million Swiss francs ($766 million), compared with $7.2 billion for Merck’s Keytruda immunotherapy and $6.7 billion for Bristol’s Opdivo.

The two rival drugs that harness the body’s own immune system to fight disease had a roughly two-year head start on Roche’s drug, which along with mounting data underscoring their effectiveness for some patients with different cancers has helped them gain a big lead in sales.

Read Also: Roche, AC Immune drop Alzheimer drug trials after setback

Opdivo is already approved in small cell lung cancer in cases where patients fail at least two other treatments, while Keytruda is now under priority FDA review, also for third-line treatment of SCLC.

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Farhat Nasim

Farhat Nasim

Farhat Nasim joined Medical Dialogue as Reporter in 2017. She Covers all the updates in the Pharmaceutical field, Policy, Insurance, Business Healthcare, Medical News, Health News, Pharma News, Healthcare and Investment. She is a graduate of St.Xavier's College Ranchi. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751


Source: Reuters
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