Pfizer Inc said a combination of its breast cancer drug, Ibrance, and another drug was not statistically significant in extending overall survival in certain patients, the secondary goal of a late-stage trial.
Ibrance is Pfizer’s blockbuster treatment and is already approved as a combination with endocrine therapy for use in breast cancer patients. The treatment brought in sales of $933 million in the first quarter of 2018.
An interim analysis of the trial in 2015 showed that the Ibrance combo had met its main goal of progression-free survival, or extending the length of time a patient lives without the disease worsening.
The company would present detailed data on the trial at an upcoming meeting.