Pfizer Abrocitinib to treat atopic dermatitis meet goals in late-stage study

Abrocitinib, which belongs to a class of drugs known as JAK inhibitors, which block inflammation-causing enzymes, known as Janus kinases, achieved statistically significant improvement in clearing the skin of patients as compared to placebo.

U.S: Pfizer Inc's new atopic dermatitis treatment met the main goals in a late-stage study that tested the drug in patients aged 12 and older with moderate to severe forms of the disease, the drugmaker said on Wednesday.

Abrocitinib, which belongs to a class of drugs known as JAK inhibitors, which block inflammation-causing enzymes, known as Janus kinases, achieved statistically significant improvement in clearing the skin of patients as compared to placebo.

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The results of the study, which tested two doses of the drug in 387 patients, showed abrocitinib was consistently well-tolerated, Pfizer said.

Abrocitinib, which received breakthrough therapy designation from the U.S. Food and Drug Administration last year, also met the secondary goals of reducing itch severity.

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