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    • NPPA fixes retail...

    NPPA fixes retail price of 59 combo drug formulations including Paracetamol, Metformin, Atorvastatin; Details

    Medical Dialogues BureauWritten by Medical Dialogues Bureau Published On 2019-11-15T16:29:45+05:30  |  Updated On 17 Aug 2021 10:40 AM IST

    New Delhi: Through a recent notification, the apex drug price regulatory agency, the National Pharmaceutical Pricing Authority (NPPA) has fixed the retail price of 59 drug formulations in combination with Paracetamol, Metformine, Atorvastatin, Rosuvastatin and others under the Drugs Prices Control Order (DPCO), 2013, exclusive of goods and services tax (GST).


    The formulations whose prices have been fixed by NPPA are combination drugs. The list mentions a combination of Acetaminophen (Paracetamol) and Tramadol Hydrochloride Tablets, Glimepiride and Metformine Tablet (Gluformin G 0.5), Telmisartan and Metoprolol Tablet, Metformin Hydrochloride, Gliclazide and Pioglitazone Tablet (Reclimet PG-60 ), Atorvastatin Calcium and Clopidogrel Capsule (MACTOR CV 10), Vildagliptin and Metformin Tablet (GLUVILDA M 500 / VIGLUCOZ M 500), Rosuvastatin and Clopidogrel Capsule, Paracetamol and Phenylephrine Sachet and so on.


    Various drugmakers including Dr Reddy's Laboratories (Dr Reddys Labs), Cipla, Torrent Pharma, Emcure, Abbott, Intas Pharma, Eris Lifesciences, Sun Pharma, Macleods Pharma, Hetero Labs, Wockhardt, Panacea Biotech are involved in manufacturing the said formulations under different brand names.


    For instance, formulations mentioned in the list is indicated for the treatment of Type 2 Diabetes, to reduce the level of bad cholesterol, treat low blood calcium levels, upset stomach, pain management drug, decrease the amount of HIV in body and so on.


    The details of the NPPA notification read;











































































































































































































































































































































































































































































































    Sl. No.Name of the
    Formulation /
    Brand Name
    Strength UnitManufacturer &
    Marketing Company
    Retail
    Price
    (Rs.)
    (1) (2) (3) (4) (5) (6)
    1.Acetaminophen
    (Paracetamol) +
    Tramadol
    Hydrochloride
    Tablets
    Each film-coated tablet contains:
    Acetaminophen IP (Paracetamol) 325mg,
    Tramadol Hydrochloride Tablets IP
    37.5mg
    1 TabletM/s Pure & Cure
    Healthcare Pvt. Ltd. / Dr.
    Reddy's Laboratories
    Ltd.
    4.91
    2.Amoxycillin +
    Potassium
    Clavulanate
    suspension
    Each 5ml Reconstituted suspension
    contains:
    Amoxycillin Trihydrate IP eq. to
    Amoxycillin 400mg,
    Potassium Clavulanate Diluted IP eq. to
    Clavulanic Acid 57mg
    1 MLM/s Medicef Pharma /
    M/s Emcure
    Pharmaceuticals Limited
    3.35
    3.Glimepiride +
    Metformine Tablet
    (Gluformin G 0.5)
    Each film-coated tablet contains:
    Glimepiride IP 0.5mg
    Metformine Hydrochloride IP 500mg (As
    prolonged-release form)
    1 TabletM/s Anphar Organics
    Private Limited / M/s
    Abbott Healthcare Pvt.
    Ltd.
    3.65
    4.Emtricitabine +
    Tenofovir
    Alafenamide Tablet
    Each film-coated tablet contains:
    Emtricitabine IP 200mg.
    Tenofovir Alafenamide Hemifumarate
    eq. to Tenofovir Alafenamide 10mg
    1 TabletM/s Hetero Labs Ltd. /
    M/s Emcure
    Pharmaceuticals Ltd.
    31.17
    5.Cefixime +
    Potassium
    Clavulanate
    suspension
    Each 5ml of reconstituted suspension
    contains:
    Cefixime IP (As Trihydrate) eq. to
    Anhydrous Cefixime 100mg,
    Potassium Clavulanate Diluted IP eq. to
    Clavulanic Acid 62.50mg
    1 MLM/s Brooks Laboratories
    Ltd. / M/s Intas
    Pharmaceuticals Limited
    3.04
    6.Calcium Carbonate +
    Vitamin D3+
    Mecobalamin + LMethylfolate +
    Pyridoxal – 5-
    Phosphate Tablet
    Each film-coated tablet contains:
    Calcium Carbonate IP 1250mg, eq. to
    Elemental Calcium 500mg,
    Vitamin D3 IP 2000 IU
    Mecobalamin IP (Methylcobalamin)
    1500mcg
    L-Methylfolate Calcium 1mg,
    Pyridoxal – 5-Phosphate 20mg
    1 TabletM/s Akums Drugs &
    Pharmaceuticals Ltd. /
    M/s Torrent
    Pharmaceuticals Ltd.
    18.58
    7.Budesonide CapsuleEach hard gelatine capsule contains: Budesonide (as controlled release
    pellets) IP 3mg
    1 CapsuleM/s Cipla Limited14.50
    8.Diclofenac
    Diethylamine +
    Methyl Salicylate +
    Menthol + Absolute
    Alcohol Spray
    Spray contains:
    Diclofenac Diethylamine IP 2.32%w/v
    eq. to Diclofenac Sodium IP 2.00%w/v,
    Methyl Salicylate IP 10% w/v,
    Menthol IP 5%w/v,
    Absolute Alcohol IP 10%v/v
    Per GM for
    25gm Pack
    M/s Pontika Aerotech
    Limited / M/s Cipla
    Limited
    3.96
    9.Dolutegravir +
    Lamivudine +
    Tenofovir Disoproxil
    Tablet
    Each film coated tablet contains:
    Dolutegravir Sodium eq. to Dolutegravir
    50mg,
    Lamivudine IP 300mg,
    Tenofovir Disoproxil Fumarate IP 300mg
    eq. to Tenofovir Disproxil 245mg
    1 TabletM/s Cipla Limited114.06
    10.Telmisartan +
    Metoprolol Tablet
    Each uncoated Bilayered Tablet contains:
    Telmisartan IP 40mg
    Metoprolol Succinate IP 23.75 eq. to
    Metoprolol Tartrate (in Prolonged
    Release form) 25mg
    1 TabletM/s Eris Lifesciences Ltd.9.93
    11.Telmisartan +
    Metoprolol Tablet
    Each uncoated Bilayered Tablet contains:
    Telmisartan IP 40mg
    Metoprolol Succinate IP 47.5 eq. to
    Metoprolol Tartrate (in Prolonged
    Release form) 50mg
    1 TabletM/s Eris Lifesciences Ltd.12.23
    12.Metformin
    Hydrochloride +
    Gliclazide +
    Pioglitazone Tablet
    (Reclimet PG-30 )
    Each uncoated bilayered tablet contains:
    Metformin Hydrochloride IP (in-sustained release form) 500mg,
    Gliclazide IP (in-sustained release form)
    30mg,
    Pioglitazone HCL IP eq. to Pioglitazone
    15mg
    1 TabletM/s Inventia Healthcare
    Ltd. / Dr. Reddy's
    Laboratories Limited
    5.98
    13.Metformin
    Hydrochloride +
    Gliclazide +
    Pioglitazone Tablet
    (Reclimet PG-60 )
    Each uncoated bilayered tablet contains:
    Metformin Hydrochloride IP (in
    sustained-release form) 500mg,
    Gliclazide IP (in-sustained release form)
    60mg,
    Pioglitazone HCL IP eq. to Pioglitazone
    15mg
    1 TabletM/s Inventia Healthcare
    Ltd. / Dr. Reddy's
    Laboratories Limited
    8.30
    14.Diclofenac
    Diethylamine +
    Methyl Salicylate +
    Menthol + Absolute
    Alcohol Spray
    Spray contains:
    Diclofenac Diethylamine IP 2.32%w/v
    eq. to Diclofenac Sodium IP 2.00%w/v,
    Methyl Salicylate IP 10% w/v,
    Menthol IP 5%w/v,
    Absolute Alcohol IP 10%v/v
    Per GM for
    55gm Pack
    M/s Pontika Aerotech
    Limited / M/s Cipla
    Limited
    3.54
    15.Dextromethorphan
    Hydrobromide +
    Chlorpheniramine
    Maleate Syrup
    Each 5ml Contains:
    Dextromethorphan Hydrobromide IP
    5mg,
    Chlorpheniramine Maleate IP 1mg
    1 MLM/s Tirupati Medicare
    Ltd. / M/s Intas
    Pharmaceuticals Limited
    1.25
    16.Dextromethorphan
    Hydrobromide +
    Chlorpheniramine
    Maleate Syrup
    Each 5ml Contains:
    Dextromethorphan Hydrobromide IP
    10mg,
    Chlorpheniramine Maleate IP 2mg
    1 MLM/s Tirupati Medicare
    Ltd. / M/s Intas
    Pharmaceuticals Limited
    0.59
    17.Gatifloxacin +
    Prednisolone Eye
    Drops
    Each ml contains:
    Gatifloxacin 3.0mg,
    Prednisolone Acetate IP 10.0mg,
    Benzalkonium Chloride Solution (as
    preservative) 0.06mg
    1 MLM/s Micro Labs Limited3.35
    18.Budesonide Nebuliser
    respule
    Each 2ml respule Contains:
    Budesonide IP 0.5mg
    Per 2ml
    Respule
    M/s Sun Pharmaceutical
    Medicare Ltd. / M/s Sun
    Pharmaceutical Industries Ltd.
    17.09
    19.Clarithromycin for
    Oral Suspension
    Each 5ml of reconstituted suspension
    contains:
    Clarithromysin coated eq. to
    Charithromycin IP 250mg
    1 MLM/s Medibios
    Laboratories Limited /
    M/s Abbott Healthcare
    Pvt. Ltd.
    5.59
    20.Metformin
    Hydrochloride +
    Glimepiride Tablet (O
    GLIMADAY FORTE 1)
    Each film-coated tablet contains:
    Metformin Hydrochloride IP 1000mg (in
    prolonged-release form)
    Glimepiride IP 1mg
    1 TabletM/s Wockhardt Limited6.61
    21.Metformin
    Hydrochloride +
    Glimepiride Tablet (O
    GLIMADAY FORTE 2)
    Each film-coated tablet contains:
    Metformin Hydrochloride IP 1000mg (in
    prolonged-release form)
    Glimepiride IP 2mg
    1 TabletM/s Wockhardt Limited9.08
    22.Pantoprazole TabletEach Dual-Release Gastro-Resistant
    tablet contains:
    Pantoprazole Sodium IP eq. to
    Pantoprazole 80mg
    1 TabletM/s Sun Pharma
    Laboratories Limited
    18.22
    23.Atorvastatin Calcium
    + Clopidogrel Capsule
    (MACTOR CV 10)
    Each hard gelatine capsule contains:
    Atorvastatin Calcium IP eq. to
    Atorvastatin 10mg (As Pellets),
    Clopidogrel Bisulphate IP eq. to Clopidogrel 75mg (As Pellets)
    1 CapsuleM/s Synokem
    Pharmaceuticals Limited
    / M/s Macleods
    Pharmaceuticals Limited
    11.14
    24.Telmisartan +
    Amlodipine +
    Hydrochlorothiazide
    Tablet (Telmiduce
    AMH)
    Each uncoated bi-layered tablet contains:
    Telmisartan IP 40mg,
    Amlodipine Besylate IP eq. to
    Amlodipine 5mg
    Hydrochlorothiazide IP 12.5mg
    1 TabletM/s Macleods
    Pharmaceuticals Limited
    8.36
    25.Darunavir + Ritonavir
    Tablet
    Each film-coated tablet contains:
    Darunavir Ethanolate eq. to Darunavir
    800mg,
    Ritonavir IP 100mg Tablet
    1 TabletM/s Hetero Labs Limited
    / M/s Emcure
    Pharmaceuticals Ltd.
    197.55
    26.Amoxycillin + Docloxacillin Capsule
    (Almox C LB)
    Each hard gelatin capsule contains:
    Amoxycillin Trihydrate IP eq. to
    Amoxycillin 250mg
    Dicloxacillin Sodium IP eq. to
    Dicloxacillin 250mg
    Lactic Acid Bacillus 2.5 billion spores
    1 CapsuleM/s Theon
    Pharmaceuticals Ltd. /
    M/s Alkem Laboratories
    Limited
    7.64
    27.Atorvastatin +
    Aspirin +
    Clopidogrel Capsule
    Each hard gelatin capsule contains:
    Atorvastatin Calcium IP eq. to
    Atorvastatin 40mg (As coloured pellets),
    Aspirin IP 75mg (As enteric coated white
    coloured pellets)
    Clopidogrel Bisulphate IP eq. to
    Clopidogrel 75mg (As two brown
    coloured film-coated, each containing
    37.5mg Clopidogrel tablet IP)
    1 CapsuleM/s Windlas Biotech
    Private Limited / M/s
    Intas Pharmaceuticals
    Limited
    12.78
    28.Glycopyrronium +
    Formoterol Dry
    powder for inhalation
    (Capsule)
    Each capsule contains:
    Glycopyrronium (as Glycopyrrolate USP)
    25mcg,
    Formoterol Fumarate (As Formoterol
    Fumarate Dihydrate) 12mcg
    1 CapsuleM/s Cipla Limited10.96
    29.Levetiracetam in
    0.82% Sodium
    Chloride Injection
    Each 100ml infusion contains:
    Levetiracetam IP 500mg
    Each PackM/s Intas
    Pharmaceuticals Limited
    98.98
    30.Levetiracetam in
    0.75% Sodium
    Chloride Injection
    Each 100ml infusion contains:
    Levetiracetam IP 1000mg
    Each PackM/s Intas
    Pharmaceuticals Limited
    160.68
    31.Levetiracetam in
    0.54% Sodium
    Chloride Injection
    Each 100ml infusion contains:
    Levetiracetam IP 1500mg
    Each PackM/s Intas
    Pharmaceuticals Limited
    222.39
    32.Vildagliptin +
    Metformin Tablet
    Each Tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 500mg
    1 TabletM/s Exemed
    Pharmaceuticals / M/s
    Zydus Healthcare
    Limited
    22.82
    33.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 500mg
    1 TabletM/s Emcure
    Pharmaceuticals Ltd.
    22.82
    34.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg,
    Metformin Hydrochloride IP 500mg
    1 TabletM/s Micro Labs Limited17.85
    35.Vildagliptin +
    Metformin Tablet
    Each uncoated tablet contains:
    Vildagliptin 50mg,
    Metformin Hydrochloride IP 500mg
    1 TabletM/s Torrent
    Pharmaceuticals Ltd.
    16.10
    36.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg,
    Metformin Hydrochloride IP 500mg,
    1 TabletM/s Natco Pharma
    Limited
    6.07
    37.Vildagliptin +
    Metformin Tablet
    (GLUVILDA M 500 /
    VIGLUCOZ M 500)
    Each film-coated tablet contains:
    Metformin Hydrochloride IP 500mg
    Vildagliptin IP 50mg
    1 TabletM/s Alkem Health Science
    / M/s Alkem
    Laboratories Ltd.
    19.54
    38.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg,
    Metformin Hydrochloride IP 500mg
    1 TabletM/s Panacea Biotec Ltd.8.48
    39.Vildagliptin +
    Metformin Tablet
    (Vildamac M50/500)
    Each film-coated tablet
    contains:Vildagliptin 50mg,
    Metformin Hydrochloride IP 500mg
    1 TabletM/s Macleods
    Pharmaceuticals Limited
    20.00
    40.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 500mg
    1 TabletM/s Ravenbhel
    Healthcare Pvt. Ltd. /
    M/s Obsurge Biotech
    Limited
    15.00
    41.Vildagliptin +
    Metformin Tablet
    Each Tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 850mg
    1 TabletM/s Exemed
    Pharmaceuticals / M/s Zydus Healthcare
    Limited
    22.68
    42.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 850mg
    1 TabletM/s Emcure
    Pharmaceuticals Ltd.
    22.68
    43.Vildagliptin +
    Metformin Tablet
    Each uncoated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 850mg
    1 TabletM/s Torrent
    Pharmaceuticals Ltd.
    16.10
    44.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 850mg
    1 TabletM/s Panacea Biotec Ltd.8.61
    45.Vildagliptin +
    Metformin Tablet
    (Vildamac M50/850)
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 850mg
    1 TabletM/s Macleods
    Pharmaceuticals Limited
    20.60
    46.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 850mg
    1 TabletM/s Ravenbhel
    Healthcare Pvt. Ltd. /
    M/s Obsurge Biotech
    Limited
    18.00
    47.Vildagliptin +
    Metformin Tablet
    Each Tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Exemed
    Pharmaceuticals / M/s
    Zydus Healthcare
    Limited
    22.94
    48.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Emcure
    Pharmaceuticals Ltd.
    23.37
    49.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Micro Labs Limited18.92
    50.Vildagliptin +
    Metformin Tablet
    Each uncoated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Torrent
    Pharmaceuticals Ltd.
    16.10
    51.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Natco Pharma
    Limited
    6.16
    52.Vildagliptin +
    Metformin Tablet
    (GLUVILDA M 1000 /
    VIGLUCOZ M 1000)
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Alkem Health Science
    / M/s Alkem
    Laboratories Ltd.
    20.83
    53.Vildagliptin +
    Metformin Tablet
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Panacea Biotec Ltd.8.70
    54.Vildagliptin +
    Metformin Tablet
    (Vildamac
    M50/1000)
    Each film-coated tablet contains:
    Vildagliptin 50mg
    Metformin Hydrochloride IP 1000mg
    1 TabletM/s Macleods
    Pharmaceuticals Limited
    21.33
    55.Cilnidipine +
    Metoprolol Succinate
    Tablet
    Each film-coated Bilayerd Tablet
    contains:
    Cilnidipine IP 10mg,
    Metoprolol Succinate IP 47.50mg eq. to
    Metoprolol Tartrate 50mg (As Extended
    Release)
    1 TabletM/s Micro Labs Limited8.89
    56.Rosuvastatin +
    Clopidogrel Capsule
    Each Hard Gelatine capsule contains:
    Rosuvastatin Calcium IP eq. to
    Rosuvastatin 10mg (As pellets),
    Clopidogrel Bisulphate IP eq. to
    Clopidogrel 75mg (As Pellets)
    1 CapsuleM/s Synokem
    Pharmaceuticals Ltd. /
    M/s Cipla Limited
    13.75
    57.Rosuvastatin +
    Clopidogrel Capsule
    Each Hard Gelatine capsule contains:
    Rosuvastatin Calcium IP eq. to
    Rosuvastatin 20mg (As pellets),
    Clopidogrel Bisulphate IP eq. to
    Clopidogrel 75mg (As Pellets)
    1 CapsuleM/s Synokem
    Pharmaceuticals Ltd. /
    M/s Cipla Limited
    18.04
    58.Linezolid SuspensionEach 5ml of reconstituted suspension
    contains:
    Linezolid IP 100mg
    1 MLM/s Innova Captab Ltd. /
    M/s Brinton
    Pharmaceuticals Limited
    3.04
    59.Paracetamol +
    Phenylephrine Sachet
    Each 6gm sachet contains:
    Paracetamol IP 500mg,
    Phenylephrine Hydrochloride IP 10mg
    1 SachetM/s Maneesh
    Pharmaceuticals Ltd.
    1.89

    Also Read: NPPA fixes retail price of 14 drug formulations; Details

    The NPPA notice further added;

    (a) The manufacturer of above-mentioned formulations i.e. "new drug" under paragraph 2(u) of the DPCO, 2013 shall fix the retail price as specified in column (6) of the table hereinabove.


    (b) The manufacturer may add goods and services tax only if they have paid actually or it is payable to the Government on the retail price mentioned in column (6) of the above-said table.


    (c) The retail price for a pack of the aforesaid formulation shall be arrived at by the concerned manufacturer in accordance with the retail price specified in column (6) of the above table as per provisions contained in paragraph 11 of the DPCO, 2013. The manufacturer shall issue a price list in Form–V from date of Notification as per paragraph 24 of the DPCO, 2013 to NPPA through IPDMS and submit a copy to State Drug Controller and dealers.


    (d) As per para 24(4) of DPCO 2013, every retailer and dealer shall display price list and the supplementary price list, if any, as furnished by the manufacturer, on a conspicuous part of the premises where he carries on business in a manner so as to be easily accessible to any person wishing to consult the same.


    (e) The above mentioned retail price is applicable only to the individual manufacturer / marketer as mentioned above i.e. who have applied for the same by submitting Form-I for price fixation / revision as stipulated under DPCO, 2013 and subject to fulfilment of all the applicable statutory requirements as laid down by the Govt. under relevant statutes/ rules, including manufacturing license permission from the Competent Authority i.e. the Central/State Licensing Authority, as may be applicable, by the concerned manufacturer/marketing companies.


    (f) In case the retail price of any of the aforesaid formulations is not complied with, as per instant price notification and notes specified hereinabove, then the concerned manufacturer/marketing company shall be liable to deposit the overcharged amount along with the interest thereon under the provisions of the DPCO, 2013 read with the Essential Commodities Act, 1955.


    (g) Consequent to the issue of ceiling price of such formulation as specified in column (2) of the above table in this notification, the price order(s) fixing ceiling or retail price, if any, issued prior to the above said date of notification, stand(s) superseded.

    AbbottAtorvastatinCiplaDPCOdrug mrpdrug pricedrug retail priceEmcureEris LifesciencesGluformingluvildaHetero LabsIntas PharmaMacleods PharmamactolmetformineNational Pharmaceutical Pricing AuthorityNPPAPanacea BiotechParacetamolReclimetSun PharmaTorrent PharmaVildagliptinWockhardt

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